Bioequivalence of two enteric coated formulations of pantoprazole in healthy volunteers under fasting and fed conditions.

Abstract

PURPOSE To compare the bioavailability of two pantoprazole (CAS 102625-70-7) formulations (40 mg pantoprazole enteric coated tablets) under fasted and fed conditions as well as to evaluate the dissolution profile in biorelevant media. METHODS The subjects received either 40 mg of the reference or of test formulation in fasting (n = 28) and fed (n=70… (More)

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