Bioequivalence of oxymorphone extended release and crush-resistant oxymorphone extended release


BACKGROUND A formulation of crush-resistant extended-release opioids may deter abuse. The purpose of this study was to evaluate the bioequivalence of oxymorphone extended-release (Oxy-ER) and a crush-resistant formulation of oxymorphone extended-release (Oxy-CRF). METHODS In three open-label, randomized studies, healthy adults at a clinical research… (More)
DOI: 10.2147/DDDT.S24372


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