Bioequivalence of a sustained-release isosorbide dinitrate formulation at steady-state.

@article{Taylor1985BioequivalenceOA,
  title={Bioequivalence of a sustained-release isosorbide dinitrate formulation at steady-state.},
  author={Trevor Taylor and Leslie F Chasseaud and R M Major and F. C. Leaf and Rainer Bonn and A. O’Kelly A. Darragh and R F Lambe},
  journal={Biopharmaceutics & drug disposition},
  year={1985},
  volume={6 2},
  pages={119-29}
}
Isosorbide 2,5-dinitrate and its pharmacologically active metabolites, isosorbide 2-nitrate and isosorbide 5-nitrate, in plasma accumulated to the predicted steady-state after five consecutive oral doses of sustained-release tablets containing 40 mg isosorbide dinitrate at 12-h intervals and after five consecutive oral doses of reference standard-release… CONTINUE READING