Bioequivalence evaluation of two brands of gliclazide 80 mg tablets (Glyzide & Diamicron)--in healthy human volunteers.

@article{Najib2002BioequivalenceEO,
  title={Bioequivalence evaluation of two brands of gliclazide 80 mg tablets (Glyzide & Diamicron)--in healthy human volunteers.},
  author={Naji M. Najib and Nasir M. Idkaidek and Muntaser Beshtawi and Mohammed Bader and Isra' Admour and S Mahmood Alam and Q H M Shawket Zaman and Ruwayda Dham},
  journal={Biopharmaceutics & drug disposition},
  year={2002},
  volume={23 5},
  pages={197-202}
}
A randomized, two-way, crossover, bioequivalence study in 24 fasting, healthy, male volunteers was conducted to compare two brands of gliclazide 80 mg tablets, Glyzide (Julphar, UAE) as test and Diamicron (Servier Industries, France) as reference product. The study was performed at the International Pharmaceutical Research Centre (IPRC), in joint venture with Speciality Hospital, Amman, Jordan. The drug was administered with 240 ml of 20% glucose solution after a 10 h overnight fasting. After… CONTINUE READING