Bioengineering neural stem/progenitor cell-coated tubes for spinal cord injury repair.

  title={Bioengineering neural stem/progenitor cell-coated tubes for spinal cord injury repair.},
  author={Tasneem Zahir and Hiroshi Nomura and Xiao Guo and Howard Kim and Charles Tator and Cindi M Morshead and Molly S Shoichet},
  journal={Cell transplantation},
  volume={17 3},
The aim of this study was to understand the survival and differentiation of neural stem/progenitor cells (NSPCs) cultured on chitosan matrices in vivo in a complete transection model of spinal cord injury. NSPCs were isolated from the subependyma of lateral ventricles of adult GFP transgenic rat forebrains. The GFP-positive neurospheres were seeded onto the inner lumen of chitosan tubes to generate multicellular sheets ex vivo. These bioengineered neurosphere tubes were implanted into a… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 33 extracted citations


Publications referenced by this paper.
Showing 1-10 of 34 references

tion , and functional recovery

  • E. C. Tsai, P. D. Dalton, M. S. Shoichet, C. H. Tator
  • Glia
  • 2007

Bioengineered trolling cell adhesion and degradation of chitosan films by N-acetylation

  • H. 23. Nomura, C. H. Tator, M. S. Shoichet
  • Biomaterials
  • 2006
1 Excerpt

Similar Papers

Loading similar papers…