Bioengineering neural stem/progenitor cell-coated tubes for spinal cord injury repair.

@article{Zahir2008BioengineeringNS,
  title={Bioengineering neural stem/progenitor cell-coated tubes for spinal cord injury repair.},
  author={Tasneem Zahir and Hiroshi Nomura and Xiao Guo and Howard Kim and Charles Tator and Cindi M Morshead and Molly S Shoichet},
  journal={Cell transplantation},
  year={2008},
  volume={17 3},
  pages={245-54}
}
The aim of this study was to understand the survival and differentiation of neural stem/progenitor cells (NSPCs) cultured on chitosan matrices in vivo in a complete transection model of spinal cord injury. NSPCs were isolated from the subependyma of lateral ventricles of adult GFP transgenic rat forebrains. The GFP-positive neurospheres were seeded onto the inner lumen of chitosan tubes to generate multicellular sheets ex vivo. These bioengineered neurosphere tubes were implanted into a… CONTINUE READING

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