Bioengineered 3D Human Kidney Tissue, a Platform for the Determination of Nephrotoxicity

@inproceedings{Desrochers2013Bioengineered3H,
  title={Bioengineered 3D Human Kidney Tissue, a Platform for the Determination of Nephrotoxicity},
  author={Teresa M Desrochers and Laura Suter and Adrian Roth and David L Kaplan},
  booktitle={PloS one},
  year={2013}
}
The staggering cost of bringing a drug to market coupled with the extremely high failure rate of prospective compounds in early phase clinical trials due to unexpected human toxicity makes it imperative that more relevant human models be developed to better predict drug toxicity. Drug-induced nephrotoxicity remains especially difficult to predict in both… CONTINUE READING