Bioenergetics of skeletal muscle in mitochondrial myopathy.

  title={Bioenergetics of skeletal muscle in mitochondrial myopathy.},
  author={D. J. E. Taylor and Graham J. Kemp and George K. Radda},
  journal={Journal of the neurological sciences},
  volume={127 2},
31Phosphorus nuclear magnetic resonance spectroscopy was used to examine skeletal muscle in 29 patients with mitochondrial myopathy, 9 male and 20 female. Gastrocnemius was investigated in 15 patients and 30 normal subjects and finger flexor muscle (flexor digitorum superficialis, fds) in 24 patients and 35 normal controls. Both muscles were studied in 10 of the patients. Results were abnormal (outside the full range of normal values) in all but 2 patients. In 86% of patients (25/29… CONTINUE READING


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