Bioenergetics of acute vasogenic edema.

  title={Bioenergetics of acute vasogenic edema.},
  author={Leslie N. Sutton and Frank A Welsh and Derek Andrew Bruce},
  journal={Journal of neurosurgery},
  volume={53 4},
The bioenergetic mechanisms of vasogenic edema were studied by measuring concentrations of adenosine triphosphate (ATP), phosphocreatine (CrP), and lactate in rapidly frozen edematous white matter in cats. When edema was produced using a cold lesion, it was found that both ATP and CrP were reduced to one-half of control values, and that lactate was elevated. When a correction was applied for dilution, however, it was found that high-energy phosphates were equal to control values, and that… CONTINUE READING