Bioenergetic Profiling of Zebrafish Embryonic Development

  title={Bioenergetic Profiling of Zebrafish Embryonic Development},
  author={Krista D. Stackley and Craig Cano Beeson and Jennifer J. Rahn and Sherine S. L. Chan},
  booktitle={PloS one},
Many debilitating conditions are linked to bioenergetic defects. Developing screens to probe the genetic and/or chemical basis for such links has proved intractable. Furthermore, there is a need for a physiologically relevant assay of bioenergetics in whole organisms, especially for early stages in life where perturbations could increase disease susceptibility with aging. Thus, we asked whether we could screen bioenergetics and mitochondrial function in the developing zebrafish embryo. We… CONTINUE READING


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