Bioelectricity and microcurrent therapy for tissue healing – a narrative review

  title={Bioelectricity and microcurrent therapy for tissue healing – a narrative review},
  author={Leon Poltawski and Tim Watson},
  journal={Physical Therapy Reviews},
  pages={104 - 114}
Abstract Background: Microcurrent therapy (MCT) uses electric currents similar to those produced by the body during tissue healing. It may be a particularly beneficial where endogenous healing has failed. Aim: To review evidence regarding microcurrent in tissue healing and the application of MCT. Methods: All peer-reviewed studies concerning microcurrent and MCT were sought, and representative literature was synthesised to indicate the scope and weight of current evidence. Results: Microcurrent… 

Microcurrent therapy in the management of chronic tennis elbow: pilot studies to optimize parameters.

Monophasic MCT of peak current intensity 50 μA applied for tens of hours may be effective in reducing symptoms and promoting tendon normalization in chronic tennis elbow and a full-scale trial of the therapy is warranted.

Electrode optimization in low intensity current simulation for tissue repair

When used with Low Intensity Current, electrotherapy can mimic the body's natural bioelectric signal to promote: healing in wounds, more resilient healed scars and tissue repair. Therefore, a

Microcurrent stimulation device as an auxiliary tool for the treatment of diseases

Empirical evidences suggest that the resistance of the skin on injured areas decreases with continuous use of microcurrent stimulation, which is specially related to pain relief.

Microcurrent as an adjunct therapy to accelerate chronic wound healing and reduce patient pain.

The results of this study show there was significant reduction in wound area and pain score during the treatment period, and the ease of use of microcurrent devices would advocate its use in accelerating wound healing.

Low Frequency Ultrasonic Versus Microcurrent Effect on Tissue Healing After Tendon Suture

Low frequency ultrasonic has more significant effect than microcurrent on decreasing wound size after tendon suture on the tissue healing of Achilles tendon after suture.

Wound healing treatment by high frequency ultrasound, microcurrent, and combined therapy modifies the immune response in rats

Therapeutic high-frequency ultrasound, microcurrent, and combined therapy changed the activity of the innate and adaptive immune system during healing process but did not accelerate the closure of the wound.

Comparative study of the application of microcurrent and AsGa 904 nm laser radiation in the process of repair after calvaria bone excision in rats

Both applications, microcurrent and laser at 904 nm, favored tissue repair in the region of bone excisions during the study period and these techniques can be used as coadjuvantes in the repair of bone tissue.

Efeitos do laser GaAlAs associado à microcorrentes na cicatrização por segunda intenção

A combination of methods induces increased collagen in the initial phase of tissue repair in rats, demonstrating the efficacy of combining phototherapy with electrotherapy on second intention healing in rats.

ffects of microcurrent therapy on excisional elastic cartilage defects n young rats dson

The treatment stimulated the proliferation and differentiation of connective tissue cells, the deposition of glycosaminoglycans and collagen, and the structural reorganization of these elements during elastic cartilage repair.



A review of the biophysical basis for the clinical application of electric fields in soft-tissue repair.

The purpose of this review is to put into proper perspective the biophysical, physiological, and clinical data pertaining to use of electricity to control wound healing, with the goal of minimizing much of the prevailing confusion.

Electrical Stimulation for Wound Healing: A Review of Evidence From In Vitro Studies, Animal Experiments, and Clinical Trials

  • L. Kloth
  • Medicine
    The international journal of lower extremity wounds
  • 2005
Clinical trials related to the responses of chronic lower extremity wounds to ES therapy are reviewed, with emphasis on wounds caused by venous insufficiency, diabetic neuropathy, and ischemia in patients with and without diabetes mellitus.

Treatment of nonunion with constant direct current.

Basic studies exploring the mechanism(s) whereby electricity induces osteogenesis are opening new vistas into the understanding of bone growth and repair, and the extension of these basic studies has far-reaching clinical implications.

Electrotherapy in tissue repair.

  • K. Lampe
  • Medicine
    Journal of hand therapy : official journal of the American Society of Hand Therapists
  • 1998

Treatment of chronic wounds by means of electric and electromagnetic fields part 1 literature review

In the present review a historical literature survey dealing with human applications of electric current for wound healing acceleration is given and greater stress was laid upon the discussion concerning the problems in designing clinical studies, rationales for the employment and possible underlying mechanisms of particular methods, and problems of evaluating their efficacy.

Effect of microcurrent electrical tissue stimulation on equine tenocytes in culture.

It is indicated that microcurrent affects the behavior of equine tenocytes in culture, but that effects may be negative or positive depending on current intensity and number of applications, therefore, results are far from conclusive with respect to the suitability of using METS to promote tendon healing in horses.

Controlling cell behavior electrically: current views and future potential.

This review aims to resolve issues by describing the historical context of bioelectricity, the fundamental principles of physics and physiology responsible for DC electric fields within cells and tissues, the cellular mechanisms for the effects of small electric fields on cell behavior, and the clinical potential for electric field treatment of damaged tissues.

Integrated processes responsible for soft tissue healing.

Low-intensity Electrical Stimulation in Wound Healing: Review of the Efficacy of Externally Applied Currents Resembling the Current of Injury

The first review of research studies on the effect of LIC on wound healing is attempted to provide an overview of current evidence on the effectiveness of LIC, and to provide protocols of treatment.