Bioelectric mechanisms in regeneration: Unique aspects and future perspectives.

  title={Bioelectric mechanisms in regeneration: Unique aspects and future perspectives.},
  author={Michael Levin},
  journal={Seminars in cell & developmental biology},
  volume={20 5},
Regenerative biology has focused largely on chemical factors and transcriptional networks. However, endogenous ion flows serve as key epigenetic regulators of cell behavior. Bioelectric signaling involves feedback loops, long-range communication, polarity, and information transfer over multiple size scales. Understanding the roles of endogenous voltage gradients, ion flows, and electric fields will contribute to the basic understanding of numerous morphogenetic processes and the means by which… CONTINUE READING
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