Biodosimetry on small blood volume using gene expression assay.

@article{Brengues2010BiodosimetryOS,
  title={Biodosimetry on small blood volume using gene expression assay.},
  author={Muriel Brengues and Brigitte Katrin Paap and Michael Bittner and S. A. Amundson and Bruce Seligmann and Ronald Korn and Ralf Lenigk and Frederic Zenhausern},
  journal={Health physics},
  year={2010},
  volume={98 2},
  pages={179-85}
}
This paper reports the development of a biodosimetry device suitable for rapidly measuring expression levels of a low-density gene set that can define radiation exposure, dose and injury in a public health emergency. The platform comprises a set of 14 genes selected on the basis of their abundance and differential expression level in response to radiation from an expression profiling series measuring 41,000 transcripts. Gene expression is analyzed through direct signal amplification using a… CONTINUE READING

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