Biodistribution study of a monoclonal antibody specific to link proteins from human cartilage.

@article{Casside1991BiodistributionSO,
  title={Biodistribution study of a monoclonal antibody specific to link proteins from human cartilage.},
  author={P Cassi{\`e}de and Joelle Vilamitjana-Amedee and Reine Bareille and Loic Vuillemin and Marie Francois Harmand},
  journal={International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology},
  year={1991},
  volume={18 8},
  pages={883-90}
}
We report the use of monoclonal antibody 6F3 prepared against link proteins from human articular cartilage to elucidate the distribution of these glycoproteins within connective and other tissues. By immunohistochemical analysis, we showed that only the Fab fragment could reach the antigenic site in human articular sections. Cross-reactivity of the antibody… CONTINUE READING