Biodistribution of gold nanoparticles in mouse lung following intratracheal instillation

  title={Biodistribution of gold nanoparticles in mouse lung following intratracheal instillation},
  author={Evaldas Sadauskas and Nicklas Raun Jacobsen and Gorm Danscher and Meredin Stoltenberg and Ulla Vogel and A Nylandsted Larsen and Wolfgang G Kreyling and H{\aa}kan Wallin},
  booktitle={Chemistry Central journal},
BACKGROUND The fate of gold nanoparticles, 2, 40 and 100 nm, administered intratracheally to adult female mice was examined. The nanoparticles were traced by autometallography (AMG) at both ultrastructural and light microscopic levels. Also, the gold content was quantified by inductively coupled plasma mass spectrometry (ICP-MS) and neutron activation analysis (NAA). The liver is the major site of deposition of circulating gold nanoparticles. Therefore the degree of translocation was determined… CONTINUE READING


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Translocation and effects of gold nanoparticles after inhalation exposure in rats

  • LE Yu, LL Yung, +6 authors W Ong
  • Nanotoxicology
  • 2007
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