Biodistribution of gold nanoparticles and gene expression changes in the liver and spleen after intravenous administration in rats.

@article{Balasubramanian2010BiodistributionOG,
  title={Biodistribution of gold nanoparticles and gene expression changes in the liver and spleen after intravenous administration in rats.},
  author={Suresh K Balasubramanian and Jinatta Jittiwat and Jayapal Manikandan and Choon-nam Ong and Liya Yu and W R Ong},
  journal={Biomaterials},
  year={2010},
  volume={31 8},
  pages={2034-42}
}
Biodistribution of gold nanoparticles (AuNPs) in more than 25 organs were examined on 1 day, 1 week, 1 month and 2 months after a single intravenous (i.v.) injection in rats. Au was rapidly and consistently accumulated in liver (49.4+/-50.4-72.2+/-40.5 ng/g) and spleen (8.4+/-5.0-9.5+/-6.4 ng/g) throughout the entire timeframe of the study (2 months… CONTINUE READING