Biodistribution of antisense nanoparticles in mammary carcinoma rat model.

Abstract

Efficient and specific delivery of antisenses (ASs) and protection of the sequences from degradation are critical factors for effective therapy. Sustained release nanoparticles (NP) offer increased resistance to nuclease degradation, increased amounts of AS uptake, and the possibility of control in dosing and sustained duration of AS administration. The… (More)
DOI: 10.3109/10717541003777225

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6 Figures and Tables