Biodistribution characteristics of mannosylated, fucosylated, and galactosylated liposomes in mice.

@article{Kawakami2000BiodistributionCO,
  title={Biodistribution characteristics of mannosylated, fucosylated, and galactosylated liposomes in mice.},
  author={Shigeru Kawakami and Joseph Wong and Atsushi Sato and Yoshiyuki Hattori and Fumiyoshi Yamashita and Mitsuru Hashida},
  journal={Biochimica et biophysica acta},
  year={2000},
  volume={1524 2-3},
  pages={258-65}
}
The in vivo disposition behavior and pharmacokinetic characteristics of galactosylated (Gal), mannosylated (Man) and fucosylated (Fuc) liposomes were compared in this study. For the preparation of the glycosylated liposomes, cholesten-5-yloxy-N-(4-((1-imino-2-beta-D-thiogalactosyle thyl)amino)a lkyl)formamide (Gal-C4-Chol) (Kawakami et al., Biochem. Biophys. Res. Commun. 252 (1998) 78-83) and its mannosylated and fucosylated derivatives (Man-C4-Chol and Fuc-C4-Chol, respectively) were… CONTINUE READING