[Biodistribution and metabolism of radio-iodinated IBZM in rats].

  • G Cao, T Tan
  • Published 2000 in
    Hua xi yi ke da xue xue bao = Journal of West…

Abstract

The aim of this study was to assess the bio-distribution and metabolic behavior of radio-iodinated IBZM in rats. Routine and improved technologies were used. The results showed that the radio-iodinated IBZM had favorable bio-distribution and metabolic behavior. The radio-distribution was high and the radio-iodinated IBZM remained long in striatum where no metabolic by-products manifested at 30 minutes after injection. These suggested that radio-iodinated IBZM is an excellent dopamine D2 receptor imaging agent for SPECT in humans, and it is stressed that thyroid must be blocked by iodine during the study of imaging.

Cite this paper

@article{Cao2000BiodistributionAM, title={[Biodistribution and metabolism of radio-iodinated IBZM in rats].}, author={G Cao and T Tan}, journal={Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao}, year={2000}, volume={31 2}, pages={171-3} }