Biodegradation of 4-(1-nonyl)phenol by axenic cultures of the yeast Candida aquaetextoris: identification of microbial breakdown products and proposal of a possible metabolic pathway

  title={Biodegradation of 4-(1-nonyl)phenol by axenic cultures of the yeast Candida aquaetextoris: identification of microbial breakdown products and proposal of a possible metabolic pathway},
  author={Giovanni Vallini and Stefania Frassinetti and Felicia D’Andrea and Giorgio Catelani and Monica Agnolucci},
  journal={International Biodeterioration \& Biodegradation},

Aerobic degradation of estrogenic alkylphenols by yeasts isolated from a sewage treatment plant

It is concluded that Candida rugopelliculosa RRKY5 is a potent candidate for the biodegradation of 4-t-OP and thus can potentially be used for bio-remedial actions in the future.

Quantification of the Influence of Extracellular Laccase and Intracellular Reactions on the Isomer-Specific Biotransformation of the Xenoestrogen Technical Nonylphenol by the Aquatic Hyphomycete Clavariopsis aquatica (cid:1)

Evidence for an unspecific oxidation of t-NP isomers was consistently obtained from laccase-expressing fungal cultures when intracellular biotransformation was suppressed and from reaction mixtures containing isolated laccases.

Role of P450 Monooxygenases in the Degradation of the Endocrine-Disrupting Chemical Nonylphenol by the White Rot Fungus Phanerochaete chrysosporium

This study provides the first evidence for the involvement of P450 enzymes in NP degradation by a white rot fungus and the first genome-wide identification of specific P450 genes responsive to an environmentally significant toxicant.

Biodegradation of phenol and 4-chlorophenol by the yeast Candida tropicalis

The results showed that the models proposed adequately described the dynamic behaviors of biodegradation by Candida tropicalis, and showed that 4-cp biodegrading velocity was higher than that without phenol.



The metabolism of 1-phenylethanol and acetophenone by Nocardia T5 and an Arthrobacter species.

The evidence suggests that catechol oxidation again proceeds by ‘ortho’ fission and the β-oxoadipate pathway, the formation of even transient amounts of cis, cis-hydroxy muconic semialdehyde has never been observed.

Microbial degradation of hydrocarbons. Catabolism of 1-phenylalkanes by Nocardia salmonicolor.

The results suggest that the main catabolic routes for 1-phenyldodecane and1-phenylnonane may converge at cinnamate, and it is proposed that 1- phenyldidecane is catabolized by omega-oxidation of the terminal methyl group, side-chain beta-oxduction to 4-phenolbutyrate and ring cleavage to maleylacetoacetate.

Screening of n -Alkylbenzenes Assimilating Yeasts and Identification of Oxidation Products from n -Alkylbenzenes

As a result of screening of n-alkylbenzenes assimilating yeasts, it was shown that the yeasts which grew well on n-alkane (C15) showed also good growth on n-alkylbenzenes (from C7 to C19 of side

Microbial conversion of ethylbenzene to 1-phenethanol and acetophenone by Nocardia tartaricans ATCC 31190

A culture of Nocardia tartaricans ATCC 31190 was capable of catalyzing the conversion of ethylbenzene to 1-phenethanol and acetophenone while growing in a shake flask culture with hexadecane as the

Metabolites of 4-n-Nonylphenol in Wheat Cell Suspension Cultures

Alkylphenol, a metabolite of nonionic surfactants, was examined for its metabolism in cell cultures of wheat according to a standardized method and the chemical structures were elucidated.

Metabolism of aloesin and related compounds by human intestinal bacteria: a bacterial cleavage of the C-glucosyl bond and the subsequent reduction of the acetonyl side chain.

The first report on the cleavage of the C-glycosyl bond of chromone C-glucosides by intestinal bacteria is reported, suggesting the importance of a free hydroxy group adjacent to theC- glucosyl group in the molecule for the bacterialCleavage of aloesin derivatives.

Mechanism for Biotransformation of Nonylphenol Polyethoxylates to Xenoestrogens in Pseudomonas putida

A mechanism for biotransformation is proposed which involves an oxygen-independent hydroxyl shift from the terminal to the penultimate carbon of the terminal ethoxylate unit of NPEOx and dissociation of the resulting hemiacetal to release acetaldehyde and the next-lower homolog, NPEO-1, which then undergoes further cycles of the same reaction until x = 2.

Isolation of a Bacterial Strain Able To Degrade Branched Nonylphenol

High-performance liquid chromatography and gas chromatography-mass spectroscopy analysis of the culture media indicated that the strain starts the degradation of NP with a fission of the phenol ring and preferably uses the para isomer of NP and not the ortho isomer.

Toxicity, uptake and metabolism of 4-n-nonylphenol in root cultures and intact plants under septic and aseptic conditions

  • Maria BokernPetra RaidH. Harms
  • Environmental Science
    Environmental science and pollution research international
  • 1998
4-Nonylphenol, a compound with estrogenic activity, has been shown to occur in sewage sludges and effluents of sludge treatment, may result in the contamination of crop plants and may therefore have an impact on the quality of food or feedstuff.

Characterization of biliary metabolites of 4-n-nonylphenol in rainbow trout (Oncorhynchus mykiss).

The metabolic profile was totally modified by beta-glucuronidase hydrolysis, showing that most of the metabolites were glucuronic acid conjugates.