Biodegradable polymer films for releasing nanovehicles containing sirolimus.

  title={Biodegradable polymer films for releasing nanovehicles containing sirolimus.},
  author={H. I. Kim and Madoka Takai and Tomohiro Konno and Ryosuke Matsuno and Kazuhiko Ishihara},
  journal={Drug delivery},
  volume={16 4},
To obtain novel biodegradable sirolimus-releasing polymer films that could release nanovehicles incorporating sirolimus, polyester, a water-soluble amphiphilic phospholipid polymer, and sirolimus were blended. The sirolimus-releasing polymer films were characterized by scanning electron microscopy and differential scanning calorimetry. Nanovehicles were formed with the phospholipid polymer chains and could be released from the sirolimus-releasing polymer films. The hydrodynamic diameter of the… CONTINUE READING


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