Biodegradable particles as vaccine antigen delivery systems for stimulating cellular immune responses.

@article{Joshi2013BiodegradablePA,
  title={Biodegradable particles as vaccine antigen delivery systems for stimulating cellular immune responses.},
  author={Vijaya Bharti Joshi and Sean M. Geary and Aliasger K Salem},
  journal={Human vaccines & immunotherapeutics},
  year={2013},
  volume={9 12},
  pages={2584-90}
}
There is a need for both new and improved vaccination formulations for a range of diseases for which current vaccines are either inadequate or non-existent. Biodegradable polymer-based vaccines fulfill many of the desired properties in achieving effective long-term protection in a manner that is safe, economical, and potentially more practicable on a global scale. Here we discuss some of the work performed with micro/nanoparticles made from either synthetic (poly[lactic-co-glycolic acid] [PLGA… CONTINUE READING
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A comparative study of the antigen-specific immune response induced by co-delivery of CpG ODN and antigen using fusion molecules or biodegradable microparticles

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