Biodegradable nanoparticles designed for drug delivery: The number of nanoparticles impacts on cytotoxicity.

@article{Mendes2015BiodegradableND,
  title={Biodegradable nanoparticles designed for drug delivery: The number of nanoparticles impacts on cytotoxicity.},
  author={L{\'i}via Palmerston Mendes and Jorge Miguel Ferreira Delgado and Angela Daniela A Costa and Marcelo de Sousa Vieira and Poliana Lopes Benfica and Eliana M Lima and Marize Campos Valadares},
  journal={Toxicology in vitro : an international journal published in association with BIBRA},
  year={2015},
  volume={29 6},
  pages={1268-74}
}
Nanostructured drug delivery systems are based on biocompatible and biodegradable components. Composition, size and membrane surface properties are characteristics that may influence cell viability in cytotoxicity assays. In this work, four nanostructured systems commonly used for drug delivery were prepared and cytotoxicity was evaluated on human lymphocytes and Balb/c 3T3 fibroblasts. The hemolytic potential was also investigated. Polymeric nanocapsules (NC) and nanospheres (NS… CONTINUE READING
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