Biodegradable fibrin conduit promotes long-term regeneration after peripheral nerve injury in adult rats.

@article{Pettersson2010BiodegradableFC,
  title={Biodegradable fibrin conduit promotes long-term regeneration after peripheral nerve injury in adult rats.},
  author={Jonas Pettersson and Daniel Felix Kalbermatten and Aleksandra M. McGrath and Liudmila N. Novikova},
  journal={Journal of plastic, reconstructive & aesthetic surgery : JPRAS},
  year={2010},
  volume={63 11},
  pages={1893-9}
}
Peripheral nerve injuries are often associated with loss of nerve tissue and require autologous nerve grafts to provide a physical substrate for axonal growth. Biosynthetic neural conduits could be an alternative treatment strategy in such injuries. The present study investigates the long-term effects of a tubular fibrin conduit on neuronal regeneration, axonal sprouting and recovery of muscle weight following peripheral nerve injury and repair in adult rats. Sciatic axotomy was performed… CONTINUE READING
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