Biodegradable dendritic positron-emitting nanoprobes for the noninvasive imaging of angiogenesis.

@article{Almutairi2009BiodegradableDP,
  title={Biodegradable dendritic positron-emitting nanoprobes for the noninvasive imaging of angiogenesis.},
  author={Adah Almutairi and Raffaella Rossin and Monica Shokeen and Aviv Hagooly and Ashwin Ananth and Benjamin J. Capoccia and Steve Guillaudeu and Dana Abendschein and Carolyn Jane Anderson and Michael J. Welch and Jean M. J. Fr{\'e}chet},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2009},
  volume={106 3},
  pages={685-90}
}
A biodegradable positron-emitting dendritic nanoprobe targeted at alpha(v)beta(3) integrin, a biological marker known to modulate angiogenesis, was developed for the noninvasive imaging of angiogenesis. The nanoprobe has a modular multivalent core-shell architecture consisting of a biodegradable heterobifunctional dendritic core chemoselectively functionalized with heterobifunctional polyethylene oxide (PEO) chains that form a protective shell, which imparts biological stealth and dictates the… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 66 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 26 references

Similar Papers

Loading similar papers…