Biodegradable calcium phosphate nanoparticles as a new vehicle for delivery of a potential ocular hypotensive agent.

@article{Chu2002BiodegradableCP,
  title={Biodegradable calcium phosphate nanoparticles as a new vehicle for delivery of a potential ocular hypotensive agent.},
  author={T. Chu and Q. He and D. Potter},
  journal={Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics},
  year={2002},
  volume={18 6},
  pages={
          507-14
        }
}
  • T. Chu, Q. He, D. Potter
  • Published 2002
  • Chemistry, Medicine
  • Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
  • The purpose of this study was to determine the efficacy of a newly prepared formulation containing biodegradable calcium phosphate nanoparticles (CAP) and 7-hydroxy-2-dipropyl-aminotetralin (7-OH-DPAT) in pigmented and non-pigmented rabbits using the surrogate end points of intraocular pressure (IOP) and aqueous flow rate. IOP (mmHg) was measured by utilizing a manometrically calibrated Mentor pneumatonometer. Rates of aqueous humor flow were measured with a Fluorotron Master by estimating the… CONTINUE READING
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    References

    SHOWING 1-10 OF 12 REFERENCES
    Ocular drug delivery of progesterone using nanoparticles.
    • 85
    Intravitreal delivery of oligonucleotides by sterically stabilized liposomes.
    • 93
    • PDF
    Biodegradable nanoparticles for targeted drug delivery in treatment of inflammatory bowel disease.
    • 328
    • PDF
    Mechanisms and sites of ocular action of 7-hydroxy-2-dipropylaminotetralin: a dopamine(3) receptor agonist.
    • E. Chu, T. Chu, D. Potter
    • Chemistry, Medicine
    • The Journal of pharmacology and experimental therapeutics
    • 2000
    • 21
    Calcium Phosphate Nanoparticle Adjuvant
    • 171
    • PDF
    Ocular hypotensive action of a dopaminergic (DA2) agonist, 2,10,11-trihydroxy-N-n-propylnoraporphine.
    • 18
    Potential sites of action of TNPA: a dopamine-2 receptor agonist.
    • 13