Biodegradable block copolymers as injectable drug-delivery systems

@article{Jeong1997BiodegradableBC,
  title={Biodegradable block copolymers as injectable drug-delivery systems},
  author={Byeongmoon Jeong and You Han Bae and Doo Sung Lee and Sung Wan Kim},
  journal={Nature},
  year={1997},
  volume={388},
  pages={860-862}
}
Polymers that display a physicochemical response to stimuli are widely explored as potential drug-delivery systems. Stimuli studied to date include chemical substances and changes in temperature, pH and electric field. Homopolymers or copolymers of N-isopropylacrylamide, and poly(ethylene oxide)–poly(propylene oxide)–poly(ethylene oxide) (known as poloxamers) are typical examples of thermosensitive polymers, but their use in drug delivery is problematic because they are toxic and non… CONTINUE READING
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