Biodegradable Nanoparticles as Vaccine Adjuvants and Delivery Systems : Regulation of Immune Responses by Nanoparticle-Based Vaccine

@inproceedings{Akagi2017BiodegradableNA,
  title={Biodegradable Nanoparticles as Vaccine Adjuvants and Delivery Systems : Regulation of Immune Responses by Nanoparticle-Based Vaccine},
  author={Takami Akagi and Masanori Baba and Mitsuru Akashi},
  year={2017}
}
Polymeric nanoand microparticles have recently been shown to possess significant potential as drug delivery systems. In particular, the use of biodegradable polymeric nanoparticles with entrapped antigens such as proteins, peptides, or DNA represents an exciting approach for controlling the release of vaccine antigens and optimizing the desired immune response via selective targeting of the antigen to antigen-presenting cells (APCs). The efficient delivery of antigens to APCs, especially in… CONTINUE READING
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