Biodegradable, Elastic Shape-Memory Polymers for Potential Biomedical Applications

@article{Lendlein2002BiodegradableES,
  title={Biodegradable, Elastic Shape-Memory Polymers for Potential Biomedical Applications},
  author={Andreas Lendlein and Robert S. Langer},
  journal={Science},
  year={2002},
  volume={296},
  pages={1673 - 1676}
}
The introduction of biodegradable implant materials as well as minimally invasive surgical procedures in medicine has substantially improved health care within the past few decades. This report describes a group of degradable thermoplastic polymers that are able to change their shape after an increase in temperature. Their shape-memory capability enables bulky implants to be placed in the body through small incisions or to perform complex mechanical deformations automatically. A smart… 
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In this chapter, the main characteristics of these materials and their applications in biomedicine are described.
Recent Advances in Shape Memory Soft Materials for Biomedical Applications.
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This review discusses the design considerations critical to the successful integration of SMPs for use in vivo, and highlights recent work on three classes of S MPs: shape memory polymers and blends, shape memory polymer composites, and shape memory hydrogels.
Shape-memory polymers as a technology platform for biomedical applications
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Controlled Drug Release from Biodegradable Shape-Memory Polymers
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Drug loading and release, drug effects on thermomechanical properties of SMPs, and drug release patterns in a physiological environment are described and potential applications in minimally-invasive surgery are discussed.
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