Biocomputing: numerical simulation of glioblastoma growth using diffusion tensor imaging.

@article{Bondiau2008BiocomputingNS,
  title={Biocomputing: numerical simulation of glioblastoma growth using diffusion tensor imaging.},
  author={Pierre-Yves Bondiau and Olivier Clatz and Maxime Sermesant and P. -Y. Marcy and Herv{\'e} Delingette and Marc Paul Frenay and Nicholas Ayache},
  journal={Physics in medicine and biology},
  year={2008},
  volume={53 4},
  pages={879-93}
}
Glioblastoma multiforma (GBM) is one of the most aggressive tumors of the central nervous system. It can be represented by two components: a proliferative component with a mass effect on brain structures and an invasive component. GBM has a distinct pattern of spread showing a preferential growth in the white fiber direction for the invasive component. By using the architecture of white matter fibers, we propose a new model to simulate the growth of GBM. This architecture is estimated by… CONTINUE READING