Biocomposite scaffolds containing chitosan/alginate/nano-silica for bone tissue engineering.

  title={Biocomposite scaffolds containing chitosan/alginate/nano-silica for bone tissue engineering.},
  author={J A Sowjanya and Jagjit Singh and T Mohita and S Sarvanan and Ambigapathi Moorthi and Narasimhan Srinivasan and Nagarajan Selvamurugan},
  journal={Colloids and surfaces. B, Biointerfaces},
Bone tissue engineering is a promising alternative method for treating bone loss by a combination of biomaterials and cells. In this study, we fabricated biocomposite scaffolds by blending chitosan (CS), alginate (Alg) and nano-silica (nSiO2), followed by freeze drying. The prepared scaffolds (CS/Alg, CS/Alg/nSiO2) were characterized by SEM, FT-IR and XRD analyses. In vitro studies such as swelling, biodegradation, biomineralization, protein adsorption and cytotoxicity were also carried out… CONTINUE READING
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