Biocompatible near-infrared quantum dots delivered to the skin by microneedle patches record vaccination

@article{McHugh2019BiocompatibleNQ,
  title={Biocompatible near-infrared quantum dots delivered to the skin by microneedle patches record vaccination},
  author={Kevin J. McHugh and Lihong Jing and Sean Y. Severt and Mache Cruz and Morteza Sarmadi and H Surangi N Jayawardena and Collin F. Perkinson and Fridrik Larusson and Sviatlana Rose and Stephanie Tomasic and Tyler Graf and Stephany Y. Tzeng and James L. Sugarman and Daniel Vlasic and Matthew Peters and Nels Peterson and Lowell Wood and Wen Tang and Jihyeon Yeom and Joe Collins and Philip A. Welkhoff and Ari Karchin and Megan W Tse and Mingyuan Gao and Moungi G. Bawendi and Robert S. Langer and Ana Jaklenec},
  journal={Science Translational Medicine},
  year={2019},
  volume={11}
}
Near-infrared fluorescent microparticles administered to the skin via dissolvable microneedle patches can record vaccine delivery. On the record Vaccines prevent disease and save lives; however, lack of standardized immunization recordkeeping makes it challenging to track vaccine coverage across the world. McHugh et al. developed dissolvable microneedles that deliver patterns of near-infrared light-emitting microparticles to the skin. Particle patterns are invisible to the eye but can be imaged… 

Trends in Drug- and Vaccine-based Dissolvable Microneedle Materials and Methods of Fabrication.

  • Lyndsey E. MooreS. VucenA. Moore
  • Biology
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
  • 2022

Transmitting Light Through Biocompatible and Biodegradable Drug Delivery Micro Needles

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A skin‐integrated optoelectronic device that incorporates an array of UVA (360 nm) light emitting diodes in layouts that match those of typical lesional plaques and in designs that couple to biocompatible, penetrating polymer microneedle light waveguides to provide optical access to deep skin is introduced.

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Transdermal Composite Microneedle Composed of Mesoporous Iron Oxide Nanoraspberry and PVA for Androgenetic Alopecia Treatment

A magneto-responsive transdermal composite microneedle (MNs) with a mesoporous iron oxide nanoraspberry (MIO), that can improve the drug delivery efficiency, was fabricated by using a 3D printing-molding method.

Engineered Microneedles for Interstitial Fluid Cell‐Free DNA Capture and Sensing Using Iontophoretic Dual‐Extraction Wearable Patch

An engineered wearable epidermal system is presented with a combination of reverse iontophoresis and MNs for rapid capture and sensing of Epstein‐Barr virus cell‐ free DNA (an important biomarker of nasopharyngeal carcinoma) and opens an innovative route for minimally invasive sampling of ISF for cell‐free DNA‐related cancer screening and prognosis.

Microneedles for painless transdermal immunotherapeutic applications.

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