Biocompatibility and levofloxacin delivery of mesoporous materials.

  title={Biocompatibility and levofloxacin delivery of mesoporous materials.},
  author={M{\'o}nica Cicu{\'e}ndez and Isabel Izquierdo-Barba and Mar{\'i}a Teresa Portol{\'e}s and Mar{\'i}a Vallet-Reg{\'i}},
  journal={European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V},
  volume={84 1},
A comparative study of mesoporous matrices designed for both drug-loading methods, impregnation (IP) and surfactant-assisted drug loading (also denoted as one-pot, OP), has been carried out evaluating their physicochemical characteristics, cell response, drug delivery profiles, and antibacterial activity. Surfactant-free (calcined) and surfactant-templated (non-calcined) mesoporous silica have been used as IP and OP starting matrices, respectively. Both non-calcined and calcined matrices do not… CONTINUE READING


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