Biocompatibility and erosion behavior of implants made of triglycerides and blends with cholesterol and phospholipids.

@article{Guse2006BiocompatibilityAE,
  title={Biocompatibility and erosion behavior of implants made of triglycerides and blends with cholesterol and phospholipids.},
  author={Clare Guse and Stephanie Koennings and Angelika Maschke and Michael C Hacker and Christian D K Becker and S{\"o}ren Schreiner and Torsten Blunk and Thilo Spruss and Achim M Goepferich},
  journal={International journal of pharmaceutics},
  year={2006},
  volume={314 2},
  pages={
          153-60
        }
}
Triglycerides are a promising class of material for the parenteral delivery of drugs and have become the focus of tremendous research efforts in recent years. The aim of this study was to investigate the biocompatibility of glyceroltripalmitate as well as the influence of cholesterol and distearoyl-phosphatidyl-choline (DSPC) on the erosion behavior of the lipid. For these investigations, two in vivo studies were carried out, in which cylindrical matrices of 2 mm diameter were manufactured and… CONTINUE READING
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A new evolving paradigm for biocompatibility

  • J. Berlin . Hilborn
  • Cytotherapy
  • 2004
Highly Influential
4 Excerpts

Hormone IGF Res

  • C. S141–S151. Guse, S. Schreiner, T. Spruß, T. Blunk, A. Goepferich
  • Phospho-
  • 2002
Highly Influential
6 Excerpts

Lipids: an alternative material for protein and peptide release, ACS Symposium Series, 879 (carrier-based drug delivery)

  • A. aschke, A. Lucke, +4 authors A. Goepferich
  • 2004

Phospho - lipids as a release modifier for triglyceride matrices

  • C. Guse, S. Schreiner, T. Spruß, T. Blunk, A. Goepferich
  • 2002
2 Excerpts

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