Biochemistry of tellurium

@article{Taylor2007BiochemistryOT,
  title={Biochemistry of tellurium},
  author={Andrew Taylor},
  journal={Biological Trace Element Research},
  year={2007},
  volume={55},
  pages={231-239}
}
  • Andrew Taylor
  • Published 2007
  • Chemistry, Medicine
  • Biological Trace Element Research
Tellurium (Te) demonstrates properties similar to those of elements known to be toxic to humans, and has applications in industrial processes, which are rapidly growing in importance and scale. It is relevant, therefore, to consider the tellurium physiology, toxicity, and methods for monitoring the element in biological and environmental specimens. Animal studies suggest that up to 25% of orally administered tellurium is absorbed in the gut. There is a biphasic elimination from the circulation… Expand
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References

SHOWING 1-10 OF 36 REFERENCES
Tellurium toxicosis in Pekin ducks
TLDR
Tellurium, as the tetrachloride, was toxic to male Pekin ducks at concentrations of 500 and 1000 ppm in the diet, resulting in heavy mortality and a marked reduction in body weights within 2 weeks, and capillary proliferation and gliosis were observed along with deposits of presumably tellurium in neuroglia. Expand
Biological effects of tellurium : a review
Although tellurium is not regarded as a true trace element, in that there is no recognized biological role for tellurium in human tissues and no clinical deficiency syndrome, nonetheless the amounts… Expand
Toxicology of selenium and tellurium and their compounds.
TLDR
A comprehensive survey of the toxicological properties of selenium andTellurium and their compounds is presented and it appears that tellurium is less toxic than selenarium, although there are exceptions to this rule. Expand
Selenium and tellurium in mice. Effects on growth, survival, and tumors.
TLDR
None of the four compounds affected the incidence of spontaneous tumors significantly, andSelenium level was increased in tissues when selenium was fed, and amyloidosis occurred more frequently in mice fed selenum than in controls or those fed tellurium. Expand
The metabolism of tellurium in rats.
TLDR
The whole-body retention of tellurium after intraperitoneal injection or gavage may be described by a sum of exponential terms and the variation with time of theTellurium content of the analysed tissues has been examined and shown to fit the whole- body retention curve. Expand
THE TOXICITY OF ORALLY INGESTED ARSENIC, SELENIUM, TELLURIUM, VANADIUM AND MOLYBDENUM
Albino rats were fed salts of arsenic, molybdenum, tellurium, vanadium and selenium at levels of 25 and 50 parts per million of the elements in their diets. Toxicity of the elements was determined by… Expand
Determination of tellurium in biological fluids by means of electrothermal vaporization-inductively coupled plasma-mass spectrometry (ETV-ICP-MS).
TLDR
The combination of a graphite furnace with programmable heating with that of inductively coupled plasma mass spectrometry (ICP-MS) is explored, which provides an efficient means of electrothermally vaporizing samples, especially when used with the recently described matrix modifier hyamine hydroxide. Expand
Interlaboratory trial on the determination of selenium in lyophilized human serum, blood and urine using hydride generation atomic absorption spectrometry
Chairman: Y. Thomassen (Norway); Members: J. Aaseth (Norway); G. Alfthan (Finland); D. Behne (FRG); H. A. Das (Netherlands); H. T. Delves (UK); R. M. Griffin (USA); M. Ihnat (Canada); V. Iyengar… Expand
Transplacental uptake of 127m Tellurium studies by whole-body autoradiography.
Whole-body autoradiographs and direct tissue counts demonstrated that, tellurium reached rat embryos during the period of teratogenic sensitivity for induction of hydrocephalus (gestation days 9–10).… Expand
Tellurium neuropathy
TLDR
The findings indicate that tellurium intoxication damages Schwann cells during a critical stage in their development, i. Expand
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