Biochemistry of proinflammatory macrophage activation

@inproceedings{Nonnenmacher2018BiochemistryOP,
  title={Biochemistry of proinflammatory macrophage activation},
  author={Yannic Nonnenmacher and Karsten Hiller},
  booktitle={Cellular and Molecular Life Sciences},
  year={2018}
}
In the last decade, metabolism has been recognized as a major determinant of immunological processes. During an inflammatory response, macrophages undergo striking changes in their metabolism. This metabolic reprogramming is governed by a complex interplay between metabolic enzymes and metabolites of different pathways and represents the basis for proper macrophage function. It is now evident that these changes go far beyond the well-known Warburg effect and the perturbation of metabolic… CONTINUE READING
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