Biochemistry and applications of aprotinin, the kallikrein inhibitor from bovine organs.

  title={Biochemistry and applications of aprotinin, the kallikrein inhibitor from bovine organs.},
  author={Hans Fritz and G Wunderer},
  volume={33 4},
The basic proteinase inhibitor from bovine organs, aprotinin (active ingredient of Trasylol) has been extensively studied with respect to its chemical, physical and biochemical properties and its inhibitory mechanism of action. It is widely used as a valuable tool for studying protein/protein interactions and protein conformation at the molecular level. There are numerous examples of the usefulness of aprotinin in biochemical and biomedical research. It has also become a valuable drug for the… CONTINUE READING
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