Biochemistry and Pharmacology of the Renin-Angiotensin System

@article{Johnston1990BiochemistryAP,
  title={Biochemistry and Pharmacology of the Renin-Angiotensin System},
  author={Prof. C. I. Johnston},
  journal={Drugs},
  year={1990},
  volume={39},
  pages={21-31}
}
Knowledge of the structure, function and distribution of the components of the renin-angiotensin-aldosterone system (RAS) and the integrated physiological role of this hormonal system is rapidly increasing, although many questions remain unanswered. The primary structure and localisation of RAS such as renin, prorenin, angiotensinogen, angiotensin-converting enzyme (ACE) and the angiotensins have now been described. Moreover, the genes for the production of renin and ACE have been cloned and… CONTINUE READING

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