author={Frank George Young},
  journal={The Indian Medical Gazette},
  pages={92 - 92}
  • F. Young
  • Published 1 February 1955
  • Education
  • The Indian Medical Gazette
The Department of Biochemistry is internationally recognized for its research and education and offers a world-class interdisciplinary research environment in a beautiful mountain setting. As part of a commitment to continuing this tradition of excellence, the department provides a graduate program that integrates opportunities for cuttingedge creative research and study across a wide range of areas including: 

Determination of molecular alignment tensors without backbone resonance assignment: Aid to rapid analysis of protein-protein interactions

It is shown that, when NMR resonances belonging to a specific amino acid type are selected either by amino acid specific labeling, by their characteristic Cα/Cβ chemical shifts or by dedicated NMR experiments, molecular alignment tensors of proteins up to 80 kDa can be determined without prior backbone resonance assignment.

2.2 CuAAC in Peptidomimetics and Protein Mimics

CuAAC can be used to combine various peptide sequences with molecular scaffolds to develop protein mimics that can find applications as synthetic vaccines and antibodies, and can be utilized toward introducing conformational constraints and stabilizing secondary structures of α-helices, β-sheets/turns, or loop-like structures.

2.5 CuAAC and Metal-Free 1,3-Dipolar Huisgen Cycloadditions in Drug Discovery

This review is intended to provide a general overview of click-chemistry-powered drug design, with dozens of successful examples resulting in the discovery of nanomolar-active 1,2,3-triazoles in every stage of drug development.