Biochemical studies support the assumption that dopamine plays a minor role in the EEG effects of nicotine

@article{Ferger1997BiochemicalSS,
  title={Biochemical studies support the assumption that dopamine plays a minor role in the EEG effects of nicotine},
  author={Boris Ferger and Klaus Kuschinsky},
  journal={Psychopharmacology},
  year={1997},
  volume={129},
  pages={192-196}
}
In a previous study, it was shown that a moderate dose of nicotine (0.2 mg/kg SC) produced a desynchronization in the EEG and a decrease of power which was not antagonized by blockade of D1-like dopamine receptors, although this EEG pattern seemed to be characteristic for activation of D1-like rather than D2-like receptors. This seemed surprising, since nicotine is known to enhance dopaminergic neurotransmission in the basal ganglia. Since there is a strong reciprocal connection between the… CONTINUE READING