Biochemical stratagem for obligate parasitism of eukaryotic cells by Coxiella burnetii.

@article{Hackstadt1981BiochemicalSF,
  title={Biochemical stratagem for obligate parasitism of eukaryotic cells by Coxiella burnetii.},
  author={Ted Hackstadt and Jennifer C. Williams},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1981},
  volume={78 5},
  pages={3240-4}
}
Coxiella burnetti, the etiologic agent of Q fever, is an oligate intracellular parasite of eukaryotes. Unlike the majority of successful bacterial parasites, which escape the bactericidal environment of the phagolysosome by various means, C. burnetii multiplies only in the phagolysosome. In view of the relatively harsh environment inhabited by C. burnetii, we have examined (i) the in vitro metabolism of glucose and glutamate by whole cells of C. burnetii under conditions designed to approximate… CONTINUE READING
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