Biochemical properties and replication of murine intracisternal A particles during early embryogenesis.

  title={Biochemical properties and replication of murine intracisternal A particles during early embryogenesis.},
  author={S S Yang and Patricia G. Calarco and Nelson A. Wivel},
  journal={European journal of cancer},
  volume={11 3},
Intracisternal A-particles in genetically diabetic mice: Identification in pancreas and induction in cultured beta cells
The cell culture results suggest that elevated intracisternal A-particle activity observed in vivo may be produced directly or indirectly by the ambient high blood glucose levels characteristic of this mutant.
Demonstration of endogenous intracisternal type a particles in early mouse zygotes
Electron microscopy was used to examine early zygotes from C57BL/6 mice aged 5-7 h after mating to provide evidence in favour of the hypothesis of IAP involvement in the processes of normal differentiation.
The association of DNA and RNA with membranes.
  • M. Moyer
  • Biology
    International review of cytology
  • 1979
Virus-like particles and related expressions in mammalian oocytes and preimplantation stage embryos
These studies showed that virus-like particle expression was stage-specific, was not the result of exogenous infection and, in spite of relatively large numbers of particles, did not interfere with normal development.


Analysis of High-Molecular-Weight Ribonucleic Acid Associated with Intracisternal A Particles
There are probably some taxonomic relationships between intracisternal A particles and oncogenic RNA viruses, and this HMW RNA is sensitive to ribonuclease digestion and alkali treatment but is resistant to Pronase treatment.
The extraction of intracisternal A-particles from a mouse plasma-cell tumor.
Evidence is presented that 40 to 50% of the total RNA in the isolated fractions was contributed by other cytoplasmic components and the remainder may have represented RNA intrinsic to the A-particles themselves; however, further studies are required to establish this point.
Deoxyribonucleic Acid Polymerase Associated with Rous Sarcoma Virus and Avian Myeloblastosis Virus: Properties of the Enzyme and Its Product
The results of both zonal and equilibrium centrifugation indicate that nascent chains of DNA are associated with the 70S viral RNA, and it is concluded that at least two enzymatic activities are under study: transcription of DNA from viral RNA and subsequent, additional synthesis of DNA.
Mechanism of carcinogenesis by RNA tumor viruses. I. An RNA-dependent DNA polymerase in murine sarcoma viruses.
A highly active and stable DNA polymerase was found in purified preparations of two murine sarcoma viruses, suggesting that the template is RNA and the product is DNA.
RNA-dependent DNA polymerase activity in five RNA viruses: divalent cation requirements.
A soluble RNA-dependent DNA polymerase activity has been released from murine leukemia particles in the presence of manganese and high detergent concentrations.
Characterization of the Products of RNA-directed DNA Polymerases in Oncogenic RNA Viruses
Several RNA tumour viruses contain an enzyme that synthesizes a DNA–RNA hybrid using the single stranded viral RNA as template. Hybridization experiments confirm that the DNA strand is complementary
Viral RNA-dependent DNA Polymerase: RNA-dependent DNA Polymerase in Virions of RNA Tumour Viruses
Two independent groups of investigators have found evidence of an enzyme in virions of RNA tumour viruses which synthesizes DNA from an RNA template, apparently the classical process of information transfer from DNA to RNA can be inverted.