Biochemical principles of small RNA pathways.

@article{Liu2010BiochemicalPO,
  title={Biochemical principles of small RNA pathways.},
  author={Qinghua Liu and Zain Paroo},
  journal={Annual review of biochemistry},
  year={2010},
  volume={79},
  pages={295-319}
}
The discovery of RNA interference (RNAi) is among the most significant biomedical breakthroughs in recent history. Multiple classes of small RNA, including small-interfering RNA (siRNA), micro-RNA (miRNA), and piwi-interacting RNA (piRNA), play important roles in many fundamental biological and disease processes. Collective studies in multiple organisms, including plants, Drosophila, Caenorhabditis elegans, and mammals indicate that these pathways are highly conserved throughout evolution. Thus… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 95 extracted citations

Small RNA pathways in Schmidtea mediterranea.

The International journal of developmental biology • 2012
View 4 Excerpts
Highly Influenced

RNAi pathways in parasitic protists and worms.

Journal of proteomics • 2011
View 5 Excerpts
Highly Influenced

Non-coding RNAs in DNA damage response.

American journal of cancer research • 2012
View 1 Excerpt
Highly Influenced

Ribonucleases as Drug Targets.

Trends in pharmacological sciences • 2018
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 146 references

The role of PACT in the RNA silencing pathway.

The EMBO journal • 2006
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…