Biochemical origins of lactaldehyde and hydroxyacetone in Methanocaldococcus jannaschii.

@article{White2008BiochemicalOO,
  title={Biochemical origins of lactaldehyde and hydroxyacetone in Methanocaldococcus jannaschii.},
  author={Robert H White},
  journal={Biochemistry},
  year={2008},
  volume={47 17},
  pages={5037-46}
}
The biochemical routes for the metabolism of methylglyoxal and the formation of lactaldehyde and hydroxyacetone in Methanocaldococcus jannaschii have been established. The addition of methylglyoxal and NADH, NADPH, F 420H 2, or DTT to a M. jannaschii cell extract stimulated the production of both lactaldehyde and hydroxyacetone. Using appropriately labeled NADH, NADPH, and F 420H 2, hydride transfer was only observed from F 420H 2 to lactaldehyde. It was shown that cell extracts of this Archaea… CONTINUE READING