Biochemical-markers for the diagnosis of bone metastasis: a clinical review.

  title={Biochemical-markers for the diagnosis of bone metastasis: a clinical review.},
  author={Qian Huang and Xuenong Ouyang},
  journal={Cancer epidemiology},
  volume={36 1},
The preferential metastasis of cancer cells to skeleton not only disrupts the process of bone remodeling and influences the therapeutic decision, but also results in severe complications. Although the current diagnosis of bone metastases (BM) relies on bone imaging techniques, they are not sensitive enough for early detection as well as they are invasive and expensive to use. Since factors derived from bone metabolism are potentially useful to diagnose metastatic bone disease in cancer patients… CONTINUE READING

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