Biochemical indications of cerebral ischaemia and mitochondrial dysfunction in severe brain trauma analysed with regard to type of lesion

@article{Nordstrm2016BiochemicalIO,
  title={Biochemical indications of cerebral ischaemia and mitochondrial dysfunction in severe brain trauma analysed with regard to type of lesion},
  author={Carl-Henrik Nordstr{\"o}m and T H Nielsen and Wilhelm Schal{\'e}n and Peter Reinstrup and Urban Ungerstedt},
  journal={Acta Neurochirurgica},
  year={2016},
  volume={158},
  pages={1231-1240}
}
The study focuses on three questions related to the clinical usefulness of microdialysis in severe brain trauma: (1) How frequently is disturbed cerebral energy metabolism observed in various types of lesions? (2) How often does the biochemical pattern indicate cerebral ischaemia and mitochondrial dysfunction? (3) How do these patterns relate to mortality? The study includes 213 consecutive patients with severe brain trauma (342 intracerebral microdialysis catheters). The patients were… CONTINUE READING
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