Biochemical implications of a three-dimensional model of monomeric actin bound to magnesium-chelated ATP.

@article{Takamoto2007BiochemicalIO,
  title={Biochemical implications of a three-dimensional model of monomeric actin bound to magnesium-chelated ATP.},
  author={Keiji Takamoto and J. K. Amisha Kamal and Mark R. Chance},
  journal={Structure},
  year={2007},
  volume={15 1},
  pages={39-51}
}
Actin structure is of intense interest in biology due to its importance in cell function and motility mediated by the spatial and temporal regulation of actin monomer-filament interconversions in a wide range of developmental and disease states. Despite this interest, the structure of many functionally important actin forms has eluded high-resolution analysis. Due to the propensity of actin monomers to assemble into filaments structural analysis of Mg-bound actin monomers has proven difficult… CONTINUE READING