Biochemical imaging of human atherosclerotic plaques with fluorescence lifetime angioscopy.

  title={Biochemical imaging of human atherosclerotic plaques with fluorescence lifetime angioscopy.},
  author={Patrick Thomas and Paritosh Pande and Fred J. Jr. Clubb and Jessie Adame and Javier A. Jo},
  journal={Photochemistry and photobiology},
  volume={86 3},
A prototype angioscopy system with fluorescence lifetime imaging microscopy (FLIM) capabilities was built and applied for biochemical imaging of human coronary atherosclerotic plaques. The FLIM angioscopy prototype consisted of a thin flexible angioscope suitable for UV-excited autofluorescence imaging, and a FLIM detection system based on a pulse sampling approach. The angioscope was composed of an imaging bundle attached to a gradient index objective lens and surrounded by a ring of… CONTINUE READING

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