Biochemical genetics of Chinese hamster cell mutants with deviant purine metabolism III. Isolation and characterization of a mutant unable to convert IMP to AMP.

Abstract

The isolation and characterization of a new mutant of Chinese ovary cells (CHO-K1) is described. This mutant, Ade-H, has the following properties: (1) it forms a new genetic complementation group; (2) it specifically requires adenine for growth and will not grow on aminoimidazole carboxamide (AIC) or hypoxanthine; (3) it accumulates IMP; (4) it cannot… (More)

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@article{Patterson1976BiochemicalGO, title={Biochemical genetics of Chinese hamster cell mutants with deviant purine metabolism III. Isolation and characterization of a mutant unable to convert IMP to AMP.}, author={Dayonna Patterson}, journal={Somatic cell genetics}, year={1976}, volume={2 1}, pages={41-53} }