Biochemical function of selenium and its relation to vitamin E.

  title={Biochemical function of selenium and its relation to vitamin E.},
  author={William G. Hoekstra},
  journal={Federation proceedings},
  volume={34 11},
Glutathione peroxidase (glutathione:H2O2 oxidoreductase, E.C., isolated from ovine and bovine erythrocytes, has recently been shown to contain 4 selenium atoms per mole, an average of 1 Se per protein subunit of about 22,000 molecular weight. Selenium deficiency in the rat, chick and sheep causes dramatic decreases in the activity of this enzyme in the tissues, but certain sites such as liver are affected more than others. Decreases in glutathione peroxidase correlate with lesions… CONTINUE READING


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