Biochemical fractionation and purification of high-molecular-mass APOBEC3G complexes.

  • Y. T. Chiu
  • Published 2011 in Methods in molecular biology


Human APOBEC3G (A3G) is a cytidine deaminase that broadly restricts the replication of many retroviruses, including HIV-1. In different cell types, cytoplasmic A3G is expressed in high-molecular-mass (HMM) RNA-protein complexes or low-molecular-mass (LMM) forms displaying different biological activities. LMM A3G has been proposed to restrict HIV-1 infection… (More)
DOI: 10.1007/978-1-61779-018-8_12


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